Page:NIOSH Manual of Analytical Methods - 1004.pdf/1

CAS: 111-44-4

RTECS: KN0875000

EVALUATION: FULL

OSHA : C 15 ppm (skin) NIOSH: 5 ppm; STEL 10 ppm (skin); carcinogen ACGIH: 5 ppm; STEL 10 ppm (skin); carcinogen (1 ppm = 5.85 mg/m 3 @ NTP)

Issue 1: 15 February 1984 Issue 2: 15 August 1994

PROPERTIES: liquid; d 1.218 g/mL @ 20 °C; BP 178 °C; MP -52 °C; VP 50 Pa (0.4 mm Hg; 530 ppm) @ 20 °C

SYNONYMS: bis(2-chloroethyl) ether; 1,1'-oxybis[2-chloroethane]; 2,2'-dichlorodiethyl ether; sym-dichloroethyl ether

SAMPLING SAMPLER:

SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)

MEASUREMENT TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

dichloroethyl ether

DESORPTION:

1 mL CS 2; stand 30 min

FLOW RATE: 0.01 to 1 L/min VOL-MIN: -MAX:

2 L @ 15 ppm 15 L

SHIPMENT:

routine

INJECTION VOLUME:

5 µL

SAMPLE STABILITY:

at least 7 days @ 25 °C [1]

TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:

200 - 225 °C 250 - 275 °C 100 - 135 °C

BLANKS:

2 to 10 field blanks per set

CARRIER GAS:

N 2 or He, 30 mL/min

COLUMN:

3 m x 3-mm ID stainless steel; 10% FFAP on 80/100 mesh DMCS Chromosorb W-AW or equivalent

CALIBRATION:

dichloroethyl ether in CS 2

RANGE:

0.15 to 4 mg per sample [2]

ACCURACY RANGE STUDIED: BIAS:

45 to 180 mg/m 3 [1] (15-L samples) - 7.61%

ESTIMATED LOD: 0.01 mg per sample [3]

ˆ ): 0.059 [1] OVERALL PRECISION (S rT ACCURACY:

± 15.7%

PRECISION (Sr):

0.007 [1]

APPLICABILITY: The working range is 1.7 to 46 ppm (10 to 270 mg/m 3) for a 15-L air sample. This method may be used for simultaneous analysis of two or more analytes by changing the chromatographic conditions (e.g., temperature programming) . High humidity during sampling will greatly reduce breakthrough volume.

INTERFERENCES: None identified. Alternate columns, e.g., 10% SP-1000 on 80/100 mesh Supelcoport, SP-2100 with 0.1% Carbowax 1500 or DB-1 fused silica capillary column may be used.

OTHER METHODS: This is Method S357 [2] in a revised format.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94