Page:NIOSH Manual of Analytical Methods - 2553.pdf/4

KET ON ES II: MET HO D 255 3, Issue 1, dated 15 M arch 200 3 - Page 4 o f 4 [3]

[4]

NIO SH [1977]. Metho ds S 10, S 12, S 13, S 15, and S 16. N IOS H M anu al of Analytical M etho ds, 2 nd, ed., V. 2. Cincinnati, OH: N ational Institute for Occup ational Safety and Health, DHEW (NIOS H) Publication No. 77-157-B. NIO SH [1977]. Do cum enta tion of NIO SH Valida tion T ests , S10 , S12 , S13 , S15 , and S16 . Cincinnati, OH: National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 77-185.

M ETH OD W RITT EN B Y: Stephanie M. Pendergrass, NIOSH/DART

TABLE 1. GENERAL INFORMATION Compound/ (Synonyms) CAS # RTECS

Fo rm ula (M .W .)

mg/m 3= 1 ppm

Expo sure Lim its NIOSH REL (ppm)

OSHA PEL (ppm)

ACGIH TLV (ppm)

@ NTP

Properties

Methyl-n-amyl-ketone (2-Heptanone) (CAS # 110-43-0) RTECS MJ5075000

C7 H1 4 O (114.19)

100

100

50

4.67

liquid; d 0.820 g/mL; BP 151 o C; VP 0.27 kPa (2 mm Hg)

Ethyl butyl ketone (3-Heptanone) (CAS # 106-35-4) RTECS MJ5250000

C7 H1 4 O (114.19)

50

50

50

4.67

liquid; d 0.818 g/mL; BP 148 o C; VP 0.53 kPa (4 mm Hg)

Mesityl oxide (4-methyl-3-penten-2-one) (CAS # 141-79-7) RTECS SB4200000

C6 H1 0 O (98.15)

10

25

15

4.01

liquid; d 0.822 g/mL; BP 129 o C; VP 1.1 kPa (8 mm Hg)

5-Methyl-3-heptanone (Ethyl amyl ketone) (CAS # 541-85-5) RTECS MJ7350000

C8 H1 6 O (128.21)

25

25

25

5.00

liquid; d 0.822 g/mL; BP 159 o C; VP 0.27 kPa (2 mm Hg)

Camphor (CAS # 76-22-2) RTECS EX1225000

C1 0 H1 6 O (152.24)

2

2

2

6.22

solid; spec. gr. 0.992 @ 25 o C; MP 174 o C; VP 0.024 kPa (0.18 mm Hg, 1470 mg/m3); sublimes

Note: All densities and vapor pressures are at 20°C unless otherwise stated.

TABLE 2. ANALYTICAL RESULTS [1] Analyte

LOD (µg)

Precision (S r)

Range (µg)

DE (Avg)

Storag e Stability (at 5 oC after 30 Days)

2-heptanone

0.5

0.025

40-1206

0.970

0.994

3-heptanone

0.7

0.031

20-603

1.004

0.984

mesityl oxide

0.3

0.014

9-276

0.950

0.993

5-methyl-3-heptanone

0.7

0.032

11-330

0.987

0.990

camphor

0.7

0.043

9-302

0.970

0.939

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition