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ACETOIN

2558

C₄H₈O₂

MW: 88.11

CAS: 513-86-0

RTECS: EL8790000

METHOD: 2558, Issue 1

EVALUATION: PARTIAL

Issue 1: 15 March 2003

OSHA: None

NIOSH: None

ACGIH: None

PROPERTIES:

liquid, solid (dimer); d= 0.9972 g/mL @

20 °C; BP= 148 °C; FP = 50°C; MP=

15°C; Miscible in water and alcohol

SYNONYMS: 3-Hydroxy-2-butanone, 2,3-butanolone, acetyl methyl carbinol, dimethylketol

SAMPLING

MEASUREMENT

SAMPLER:

Anasorb CMS Solid Sorbent Tubes (150/75 mg)

FLOW RATE:

0.01 to 0.2 L/min

VOL-MIN:

1L

-MAX:

10 L

SHIPMENT:

Ship cold (5°C) and store in dark

SAMPLE

STABILITY:

30 days @ 5°C

BLANKS:

10% of field samples

ACCURACY

RANGE STUDIED:

Not Determined

BIAS:

Not Determined

OVERALL PRECISION(Ŝ_rT):

Not Determined

ACCURACY:

Not Determined

TECHNIQUE:

GAS CHROMATOGRAPHY, FID

ANALYTE:

Acetoin

DESORPTION:

1 mL of acetone/methanol (95:5) on rotary mixer for 1.5 hours

INJECTION

VOLUME:

1µL

TEMPERATURE

-INJECTION:

225°C

-DETECTOR:

250°C

-COLUMN:

35°C (hold 3 min) to 200°C (6°C/min)

CARRIER GAS:

He (2.8 mL/min)

COLUMN:

Capillary, fused silica, 30 m x 0.32-mm

ID; 1-µm film, Stabilwax-DA or equivalent

CALIBRATION:

Standard solutions in acetoin in

acetone/methanol (95:5) solvent

RANGE:

3 to 378 µg

ESTIMATED LOD:

1.0 µg

PRECISION(S̄_r):

0.008

APPLICABILITY: The working range for acetoin was 0.6 to 75.6 mg/m³ for a 5L air sample.

INTERFERENCES: Any compounds with similar retention times to acetoin.

OTHER METHODS: None determined.

NIOSH Manual of Analytical Methods (NMAM), Fourth Edition