Page:NIOSH Manual of Analytical Methods - 5510.pdf/1
CHLORDANE
C10 H6Cl8
MW: 409.80
METHOD: 5510, Issue 2
5510
CAS: 57-74-9
RTECS: PB9800000
EVALUATION: FULL
OSHA : 0.5 mg/m 3 (skin) NIOSH: 0.5 mg/m 3 (skin); carcinogen; Group I Pesticide ACGIH: 0.5 mg/m 3 (skin), suspect human carcinogen
Issue 1: 15 May 1989 Issue 2: 15 August 1994
PROPERTIES:
liquid; d 1.59 to 1.63 g/mL @ 25 °C; BP 175 °C; VP 0.0013 Pa (1.0 x 10 -5 mm Hg) @ 20 °C
SYNONYMS: 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane and isomers; Toxichlor; Octachlor
SAMPLING SAMPLER:
MEASUREMENT
FILTER AND SOLID SORBENT TUBE (0.8-µm cellulose ester membrane; Chromosorb 102, 100/50 mg)
FLOW RATE:
0.5 to 1 L/min
VOL-MIN: -MAX:
10 L @ 0.5 mg/m 3 200 L
SHIPMENT:
routine
SAMPLE STABILITY:
> 1 week @ 25 °C [1]
FIELD BLANKS:
2 to 10 field blanks per set
MEDIA BLANKS:
2 per set
BULK SAMPLE:
required
TECHNIQUE:
GAS CHROMOTOGRAPHY, ELECTRON CAPTURE DETECTOR (GC/ECD)
ANALYTE:
Chlordane
EXTRACTION:
10 mL toluene, stand 30 min
INJECTION VOLUME: 2 µL TEMPERATURE-INJECTION: -DETECTOR: -COLUMN: CARRIER GASES: mL/min COLUMN:
RANGE: 3
RANGE STUDIED:
0.16 to 1.17 mg/m [1,2] (120-L samples)
BIAS:
3.0%
ˆ rT): OVERALL PRECISION (S
0.070 [1,2]
ACCURACY:
± 15.3%
95% argon/5% methane @ 75
2 m x 4-mm ID glass packed with 1.5%, SP2250/1.95% SP2401 on 100/120 mesh
CALIBRATION:
ACCURACY
250 °C 300 °C 205 °C
solution of analyte in toluene or hexane with internal standard 5 to 150 µg per sample [2]
ESTIMATED LOD: 0.1 µg per sample [3] PRECISION (Sr):
0.02 @ 6 to 120 µg per sample [2]
APPLICABILITY: The working range is 0.04 to 1.2 mg/m 3 for a 120-L sample. Chlordane, accompanied by a mixture of penta-, hexa-, hepta-, and nonachlorinated compounds, is defined by a group of five chromatographic peaks. It is necessary to de termine the percentage of Chlordane and its isomers in the standards used.
INTERFERENCES: None identified; an alternate column is 2 m x 2-mm ID glass packed with 3% QF-1 on 100/120 mesh Chrom Q.
OTHER METHODS: This is NIOSH method S278 in a revised format. [2]
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94